Atopic
dermatitis, or eczema, is a common skin disease that isoften associated with
other atopic disorders, such as allergic rhinitis and asthma.
One hypotheses
concerning the mechanism of atopic dermatitis that the primary defect resides
in an immunologic disturbance thatcauses IgE-mediated sensitization, with epithelialbarrier
dysfunction regarded as aconsequence of the local inflammation.
Calophylluminophyllumextract(CIE) has been used in oriental medicines and many
previous studies reported its antimicrobial and anti-inflammatory effect via
cyclooxygenase inhibitions.
This study
examined whether the CIE exerting anti inflammation could alleviate the
symptoms of atopicdermatitis (AD) induced with 2,4-dinitrochlorobenzene(DNCB)
in mice.
