Atopic dermatitis, or eczema, is a common skin disease that
isoften associated with other atopic disorders, such as allergic rhinitis and
asthma.
One hypotheses concerning the mechanism of atopic dermatitis
that the primary defect resides in an immunologic disturbance thatcauses
IgE-mediated sensitization, with epithelialbarrier dysfunction regarded as
aconsequence of the local inflammation. Calophylluminophyllumextract(CIE)
has been used in oriental medicines and many previous studies reported its
antimicrobial and anti-inflammatory effect via cyclooxygenase inhibitions.
This study examined whether the CIE exerting anti inflammation could alleviate the symptoms of atopicdermatitis (AD) induced with 2,4 dinitrochlorobenzene(DNCB) in mice.
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