Friday, 30 June 2017

Measurement of Cuffless Blood Pressure by Using a Magnetoplethysmogram Pulsimeter

The brain’s vasculature relies on the central aorta, and there is a direct correlation betweenatherosclerosis of the central aorta and that of the neurovascular system.

Magnetoplethysmogram Pulsimeter
This relation between the brain’s vascular system and the central aorta has been evaluated recently in terms of the central arterial pressure (CAP) and the compliance of aorta. In the United States, there are 50 million hypertension patients, and 3 million patients exhibit normal self-adjustment, making them similar to patients with normal blood pressure (BP). The remaining patients exhibit malfunctioning self-adjustment. Clinical trials suggest that patients with high-resistance hypertension are more likely to develop cerebral thrombosis compared to patients with normal-resistance hypertension, when both groups are treated to the same extent by using anti-hypertension medication.



Thursday, 29 June 2017

Assessment of Glomerular Filtration Rate in Older Adults in Brazil

The global life expectancy increase has paralleled with an increase in the number of CKD cases. Serumcreatinine has been widely used to assess renal function.

However, the creatinine production rate is low in elderly people due to the muscle mass decrease related to age. Therefore, the serum creatinine might not be a satisfactory parameter for the renal function assessment in the elderly. Equations to estimate glomerular filtration rate (GFR) are a more reliable and accurate method to assess the renal function. The most widely used in clinical practice are the Modification of Diet in Renal Disease (MDRD) and the Cockcroft-Gault (CG) equations.



Wednesday, 28 June 2017

The Impact of Risk Factors on the Diastolic Dysfunction in Patients with Hypertension

Hypertension (HTA) is a global worldwide problem and is at the basis of many, primarily cardiac disease. The first changes that hypertension causes on the heart are structuraland geometric adaptation changes.

Hypertension
These changes cause dilatation and/or hypertrophy of the left ventricle (LV), that is remodeling LV, and they are accompanied by differences in cardiac function and hemodynamics. Compensatory mechanism for hemodynamic load is the increase in mass due to the hypertrophy of existing myocytes rather than hyperplasia as a result of increase in myocyte width for parallel extensions sarcomeres which results in an increase in wall thickness.



Tuesday, 27 June 2017

Love Hormone and Male Infertility

The function of oxytocin, the love hormone, in the male reproductivesystem remains ambiguous as of yet. Recent studies have revealed that reduced level of the hormone is often concurrent with infertility.

Male Infertility
It has also been found that infertility that may be attributed to low sperm count or low mobility or structural abnormality, all have significantly low concentrations of the hormone. The elucidations of the specific pathways that may cause this are yet to be explored.









Friday, 9 June 2017

Thoracic Intradural Disc Herniation: Key Considerations in Operative Management

Intradural Disc Herniation
A case presentation of intradural T11/12 disc with particular reference to the operative management, to emphasise the importance of identifying these rare cases and identify important operative considerations.

An 80 year old gentleman presented clinic with acute onset back and leg pain. He described pain in the L4 dermatomal distribution to both legs, with normal bladder and bowel function.

Lower limb power was normal, L3/4 reflexes were reduced and there were no signs of cord compression. MRI was performed which demonstrated a T11/12 disc prolapse with a possible intradural element.

Friday, 2 June 2017

Social Impairment and Mental Health

Mental Health
Stress resulting from living in large cities (and alienation in certain individuals) fuels the high incidence of psychiatric illnesses in modern metropolises.

Some pathology as Schizophrenia and Asperger has deficits on social cognition mechanisms and its presentation may be influenced by social environmental impact.

Even more, common mental disease such as depression and personality disorders has a great impact by environmental social deficits and present poor social cognition performances on some specific areas.