The global life expectancy
increase has paralleled with an increase in the number of CKD cases. Serumcreatinine has been widely used to assess renal function.
However, the creatinine
production rate is low in elderly people due to the muscle mass decrease
related to age. Therefore, the serum creatinine might not be a satisfactory
parameter for the renal function assessment in the elderly. Equations to
estimate glomerular filtration rate (GFR) are a more reliable and accurate
method to assess the renal function. The most widely used in clinical practice
are the Modification of Diet in Renal Disease (MDRD) and the Cockcroft-Gault
(CG) equations.
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