Wednesday, 28 June 2017

The Impact of Risk Factors on the Diastolic Dysfunction in Patients with Hypertension

Hypertension (HTA) is a global worldwide problem and is at the basis of many, primarily cardiac disease. The first changes that hypertension causes on the heart are structuraland geometric adaptation changes.

Hypertension
These changes cause dilatation and/or hypertrophy of the left ventricle (LV), that is remodeling LV, and they are accompanied by differences in cardiac function and hemodynamics. Compensatory mechanism for hemodynamic load is the increase in mass due to the hypertrophy of existing myocytes rather than hyperplasia as a result of increase in myocyte width for parallel extensions sarcomeres which results in an increase in wall thickness.



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